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Dr. Frank Dieterle
Personal
Data
| Date of
birth |
October
8th, 1973 |
| Place of birth |
Tübingen |
| Nationality |
German |
| Marital status |
single |
Education
and Professions
| Since September, 2005 |
Project manager in the field of biomarker development at Novartis Pharma AG in Basel |
| October, 2003 - August, 2005 |
Research in the field of metabolic profiling and biomarker identification (metabonomics) at F.
Hoffmann-La Roche Ltd. in Basel |
| July 26th,
2003 |
Ph.D. (0.75, summa cum
laude) |
| February, 2000 - July,
2003 |
Ph.D. thesis
"Integration of artificial neural networks, genetic algorithms
and chemometrics for the data analysis of sensors" in the research
group Prof. Dr. G. Gauglitz |
| January, 2000 - August,
2003 |
Scientific employee
at the Institute of Physical
and Theoretical Chemistry, Universität Tübingen |
| January 7th,
2000 |
Diplom-Chemiker (M.Sc.
Chemistry, 1.0) |
| 1999-2000 |
Master thesis "Multivariate
Datenanalyse" in the research group Prof.
Dr. G. Gauglitz |
| October 12th,
1995 |
Diplomvorprüfungen,
(B.Sc. Chemistry, 1.0) |
| 1993-2000 |
Student of general
chemistry at the Eberhard-Karls-Universität
Tübingen |
| Mai 11th, 1993 |
Abitur, (High School
Graduation, 1.0) |
| 1984-1993 |
Geschwister-Scholl-Schule
in Tübingen |
| 1981-1984 |
Primary school in Tübingen |
Career
Related Activities and Experiences
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Project management in the field of biomarker development for diagnosis, safety and therapy at Novartis Pharma AG.
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Implementation of metabonomics, metabolic profiling and biomarker identification in early drug development and in clinical phase I studies at F. Hoffmann-La Roche Ltd working in the group of Dr. Hans Senn.
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Invention and development of improved data analysis procedures and modeling techniques for NMR spectra and biomedical data.
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Identification and quantification of biomarkers and metabolites in biofluids in collaboration with NMR and LC-MS spectroscopists.
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Correlation of biomarkers and metabolites with findings from histopathology, changes of physiology, affected pathways and mechanistic toxicity.
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Biochemical and physiological interpretation of affected pathways and metabolites.
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Creation and maintenance of databases for spectra and metabolites.
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Practical and theoretical experiences in various instrumental analysis methods in the field of chromatography and spectroscopy.
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Data mining, pattern recognition and classification of various metabonomic, analytical, sensory and clinical data sets.
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Optimization of analytical methods, product compositions, immunoassays and sensor coatings by the use of experimental designs, response surface modeling and statistical analysis.
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Team leader of a group of Ph.D. students at university in the area of chemical sensors.
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Intensive courses in Analytical Chemistry with practical courses in analytical methods and separation techniques during studies at university.
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Lectures for students and participants from industry on statistics and on data analysis.
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Awarded by the “Procter & Gamble Research Award 2003” for best Ph.D. thesis.
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Project proposal, negotiations and management of the EU project AWACSS.
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Organization of the 2. Biosensor Symposium 2001, held in Tübingen from April 1st to April 3rd 2001 with 250 participants.
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Reviewer for the journals “Analytical and Bioanalytical Chemistry”, “Analytica Chimica Acta” and “Artificial Intelligence in Medicine”.
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Experienced in the programming languages Matlab (good knowledge), Delphi (good knowledge) and Perl (basic knowledge).
Languages
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German (native)
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English (fluently)
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French (basic knowledge)
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Latin (Großes Latinum)
Hobbies
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About Me